NephroCheck Test Resources
Publications on TIMP-2 & IGFBP-7


Association of renal stress/damage and filtration biomarkers with subsequent AKI during hospitalization among patients presenting to the emergency department.
Kimmel M et al.

TIMP-2*IGFBP-7 biomarker panel accurately predicts acute kidney injury in high-risk surgical patients.
Gunnerson KJ et al.

Reference intervals of urinary AKI markers IGFBP-7*TIMP-2 in apparently healthy subjects and chronic comorbid subjects without AKI.
Chindarkar NS et al.

Analytical characteristics of a biomarker-based risk assessment test for acute kidney injury (AKI).
Uetwiller-Geiger DL et al.


Urinary biomarkers TIMP-2 and IGFBP-7 early predict acute kidney injury after major surgery.
Gocze I et al.

Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial.
Zarbock A et al.

Quantification of urinary TIMP-2 and IGFBP-7: an adequate diagnostic test to predict acute kidney injury after cardiac surgery?
Wetz AJ et al.


Acute kidney injury: new biomarkers detect risk for this silent killer.
Uettwiller-Geiger DL et al.


Urinary [TIMP-2]*[IGFBP-7] for early prediction of acute kidney injury after coronary artery bypass surgery.
Pilarczk K et al.

Urinary TIMP-2*IGFBP-7 predicts adverse outcome in pediatric acute kidney injury.
Westhoff JH et al.

Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication.
Bihorac A et al.

Tissue inhibitor metalloproteinase-2 (TIMP-2) IGF-binding protein-7 (IGFBP-7) levels are associated with adverse long-term outcomes in patients with AKI.
Koyner JL et al.

Urinary TIMP-2 and IGFBP-7 as early biomarkers of acute kidney injury and renal recovery following cardiac surgery.
Meersch M et al.

Derivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers.
Hoste EA et al.


Validation of cell-cycle arrest biomarkers for acute kidney injury after pediatric cardiac surgery.
Meersch M et al.

Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.
Kashani K et al.
Podcasts

SCCM Pod -275 44th Critical Care Congress: Is Repair After AKI Linked to Long-Term Outcomes?
Interview with Dr. John Kellum

SCCM Pod-269 National Surgical Quality Improvement Program Underestimates Risk Associated with Mild and Moderate Postoperative AKI.
Interview with Dr. Azra Bihorac and Dr. Charles E. Hobson
The Science Behind AKI


Impact of perioperative acute kidney injury as a severity index for thirty-day readmission after cardiac surgery.
Brown JR et al.

Costs and outcomes of acute kidney injury (AKI) following cardiac surgery.
Dasta JF et al.

Acute kidney injury recovery pattern and subsequent risk of CKD: an analysis of Veterans Health Administration data.
Heung M et al.



Raising awareness of acute kidney injury: a global perspective of a silent killer.
Lewington AJP et al.

Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference.
McCullough PA et al.

International Society of Nephrology’s 0by25 Initiative for Acute Kidney Injury (Zero Preventable Deaths by 2025): a human rights case for nephrology.
Mehta R et al.

National Confidential Enquiry into Patient Outcome and Death. Adding Insult to Injury.
NCEPOD.org.uk